Neuroscience Reagents and Kits
ABclonal Technology Doublecortin Rabbit mAb
This gene encodes a protein from the doublecortin family containing two doublecortin domains that bind microtubules It plays a key role in cortical neuron migration during development by regulating microtubule organization and stability The protein interacts with LIS1 the regulatory subunit of platelet-activating factor acetylhydrolase which is essential for microtubule function in the cortex Mutations in this gene disrupt neuronal migration leading to cortical layering defects and conditions such as epilepsy cognitive disability double cortex syndrome in females and lissencephaly (smooth brain syndrome) in males Multiple transcript variants producing different isoforms have been identified for this gene
Cayman Chemical Aldosteron AChE Tracer 100dtn
A steroidal glycoside with diverse biological activities reduces the proliferation of LNCaP and T47D cancer cells (IC50s 32.1 and 27.5 UM respectively) inhibits TNF-a-induced nuclear translocation of NF-KB in HaCaT keratinocytes at 50 nM decreases AST serum levels in a mouse model of carbon tetrachloride-induced liver injury at 0.1 mg/kg topical administration reduces ear epidermal thickness and scaling as well as leukocyte and macrophage infiltration in an imiquimod-induced mouse model of psoriasis at 5 mg/kg
Cayman Chemical Testosteron AChE Tracer 500dtn
An agonist of GLP-1R (Ki 1.1 nM for the human receptor) induces cAMP accumulation in CHO-K1 cells expressing human GLP-1R (EC50 0.06 nM) decreases blood levels of glucose and increases blood levels of insulin in an oral glucose tolerance test in Zucker diabetic obese rats at 1 mg/animal per week reduces blood levels of GIP plasma levels of triglycerides and body weight in the same model
Cayman Chemical Substnce P AChE Tracer 100dtn
A cell-based luciferase reporter assay for human insulin receptor isoform B (INSRb)
ABclonal Technology Nestin Rabbit pAb
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
ABclonal Technology Nestin Rabbit pAb
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
Cellular Dynamics International FUJIFILM CELLULAR DYNAMICS INC
NC3922049 ICELL SENSORY NEURONS 21527
